Gunthorpe, Martin J.: search on Z-Library

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1

Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

Fergal N McNamara, Andrew Randall, Martin J Gunthorpe

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 262 KB

english, 2005

2

An animal model of chronic inflammatory pain: Pharmacological and temporal differentiation from acute models

Alex W. Wilson, Stephen J. Medhurst, Claire I. Dixon, Nick C. Bontoft, Lisa A. Winyard, Kim T. Brackenborough, Jorge De Alba, Christopher J. Clarke, Martin J. Gunthorpe, Gareth A. Hicks, Chas Bountra,

Journal:

European Journal of Pain

Year:

2006

Language:

english

File:

PDF, 462 KB

english, 2006

3

Ototrauma induces sodium channel plasticity in auditory afferent neurons

Alistair G. Fryatt, Mike Mulheran, Julie Egerton, Martin J. Gunthorpe, Blair D. Grubb

Journal:

Molecular and Cellular Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

4

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Harshad K. Rami, Mervyn Thompson, Geoffrey Stemp, Steve Fell, Jeffrey C. Jerman, Alexander J. Stevens, Darren Smart, Becky Sargent, Dominic Sanderson, Andrew D. Randall, Martin J. Gunthorpe, John B. D

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 290 KB

english, 2006

5

Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential

Laetitia Mony, James NC Kew, Martin J Gunthorpe, Pierre Paoletti

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 432 KB

english, 2009

6

The diversity in the vanilloid (TRPV) receptor family of ion channels

Martin J. Gunthorpe, Christopher D. Benham, Andrew Randall, John B. Davis

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

7

TRPV channels as temperature sensors

Christopher D. Benham, Martin J. Gunthorpe, John B. Davis

Journal:

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

8

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

Davis, John B., Gray, Julie, Gunthorpe, Martin J., Hatcher, Jonathan P., Davey, Phil T., Overend, Philip, Harries, Mark H., Latcham, Judi, Clapham, Colin, Atkinson, Kirsty

Journal:

Year:

2000

Language:

english

File:

PDF, 305 KB

english, 2000

9

TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation

Sarah C. Lappin, Andrew D. Randall, Martin J. Gunthorpe, Valerie Morisset

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 435 KB

english, 2006

10

The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: Implications for clinical use

Charles H. Large, David M. Sokal, Astrid Nehlig, Martin J. Gunthorpe, Raman Sankar, Christopher S. Crean, Kevan E. VanLandingham, H. Steve White

Journal:

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

11

The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy

Martin J. Gunthorpe, Charles H. Large, Raman Sankar

Journal:

Year:

2012

Language:

english

File:

PDF, 654 KB

english, 2012

12

The 4′lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors

Martin J. Gunthorpe, John A. Peters, Catherine H. Gill, Jeremy J. Lambert, Sarah C. R. Lummis

Journal:

The Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 248 KB

english, 2000

13

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1

Philip Hayes, Helen J Meadows, Martin J Gunthorpe, Mark H Harries, D.Malcolm Duckworth, William Cairns, David C Harrison, Catherine E Clarke, Kathryn Ellington, Rab K Prinjha, Amanda J.L Barton, Andre

Journal:

Year:

2000

Language:

english

File:

PDF, 591 KB

english, 2000

14

Discovery of small molecule antagonists of TRPV1

Harshad K Rami, Mervyn Thompson, Paul Wyman, Jeffrey C Jerman, Julie Egerton, Stephen Brough, Alexander J Stevens, Andrew D Randall, Darren Smart, Martin J Gunthorpe, John B Davis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 339 KB

english, 2004

15

Peripheral TRPV1 Receptors As Targets for Drug Development: New Molecules and Mechanisms

Szallasi, Arpad, Gunthorpe, Martin

Journal:

Current Pharmaceutical Design

Year:

2008

Language:

english

File:

PDF, 270 KB

english, 2008

16

Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1)

Martin J. Gunthorpe, Mark H. Harries, Rab K. Prinjha, John B. Davis, Andrew Randall

Journal:

The Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 248 KB

english, 2000

17

S1665 Attenuation of Inhibitory Responses to Colorectal Distension Within the Thalamus By Alosetron: Role of 5-HT2B vs 5-HT3 Receptors

Woods, Amanda J., Bulmer, David C., Evans, Martyn L., Lowe, Andrew, Gregory, Lloyd J., Gunthorpe, Martin J., Lee, Kevin, Aziz, Qasim, Williams, Steven C., Winchester, Wendy J.

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 87 KB

english, 2008

18

The therapeutic potential of TRPV1 (VR1) antagonists: clinical answers await

Harshad K. Rami, Martin J. Gunthorpe

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2004

Language:

english

File:

PDF, 190 KB

english, 2004

19

Diltiazem causes open channel block of recombinant 5-HT3 receptors

Martin J. Gunthorpe, Sarah C. R. Lummis

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 217 KB

english, 1999

20

Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway

Martin J. Gunthorpe, Boris A. Chizh

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

21

Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology

Darren Smart, Jeffrey C Jerman, Martin J Gunthorpe, Stephen J Brough, Jennie Ranson, William Cairns, Philip D Hayes, Andrew D Randall, John B Davis

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 146 KB

english, 2001

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